Figure 2From: Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3β?Irs2 gene deletion significantly decreases kidney-to-body weight ratio. Left kidney weights of 5-6 wk old (A) male and (B) female Irs2+/+ (open bars), Irs2+/- (hatched bars) and Irs2-/- (filled bars) mice were measured at the time of sacrifice. Kidney-to-body weight ratios were calculated for (C) male and (D) female groups and expressed as g/kg. Data were plotted as mean +/- SEM (n = 7-8 for each group).Back to article page