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Figure 3 | BMC Developmental Biology

Figure 3

From: Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome

Figure 3

Overall placental architecture of the DelTel7/IC2KO placentae at E14.5 by representative H&E and ISH. A) H&E stain of DelTel7/IC2KO placentae (n = 5) compared with wild type (+/+; n = 5). Scale bar: 1 mm. B) Zoom-in of boxed regions in panel A. Scale bar: 0.5 mm. C) Analysis of Prl3b1 (Pl-II) expression by ISH of DelTel7/IC2KO placentae (n = 5) compared with wild type (n = 6). Scale bar: 0.25 mm. D) Tpbpa (4311) ISH of DelTel7/IC2KO placentae (n = 4) compared with wild type (n = 4) Scale bar: 0.25 mm.

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