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Table 2 Notch112f/tm1Conpups may survive to birth

From: Effects of varying Notch1 signal strength on embryogenesis and vasculogenesis in compound mutant heterozygotes

Stage

12f/12f × +/tm1Con

   

12f/12f × +/lbd

 

Litters

Pups

+/12f

12f/tm1Con

   

Litters

Pups

+/12f

12f/lbd

E9.5

3

23

11

12

   

5

38

18

20

E10.5

3

23

13

10

   

8

70

37

33

E11.5

4

24

16

8

   

7

48

28

20

E12.5

5

25

21

4

   

8

33

28

5

E13.5

5

27

21

6

   

5

23

23

0

E15.5

3

13

9

4

   

-

-

-

-

E17.5

5

19

17

2

   

-

-

-

-

P1

6

25

23

2

   

-

-

-

-

Wean

13

50

50

0

   

8

30

30

0

  1. Embryos (E9.5 -- E17.5), post-natal pups (P1) and mice after weaning were genotyped from crosses of Notch112f/12ffemale × Notch1+/tm1Conmale or crosses of Notch112f/12ffemale × Notch1+/lbdmale. The data from Notch1+/12f× Notch112f/lbdcrosses were previously published [12] but are included for ease of comparison.