| Groups of females | |||
---|---|---|---|---|
Indices | Control | CP (12.5 mg/kg) | CP (20 mg/kg) | CP (40 mg/kg) |
Number of pregnant females | 8 | 10 | 14 | 10 |
Implantation sites/litter | 66/8.3 | 84/8.4 | 106/7.6 | 83/8.3 |
Percent of resorptions (arcsine, mean ± SE) | 6.1 (16.2 ± 3.4) a | 4.8 (15.4 ± 2.5) a | 13.2 (23.5 ± 3.6)a | 26.5 (32.0 ± 2.0) b |
Number of live fetuses | Â | Â | Â | Â |
Total | 62 | 80 | 92 | 61 |
p53+/+ | 18 (29%) | 14 (17.5%) | 16 (17.4%) | 18 (29.5%) |
p53+/- | 27 (43.6%) | 46 (57.5%) | 48 (52.2%) | 36 (59%) |
p53-/- | 17 (27.4%) | 20 (25%) | 28 (30.4%) | 7 (11.5%) |