Table 2 Proteins With Significant Changes In Expression After Inhibition of NF-κB Nuclear Translocation*
From: The functional genomic response of developing embryonic submandibular glands to NF-kappaB inhibition
Protein | Fold-Change | Function (Fig. 1) |
|---|---|---|
PCNA | 3.7↓ | cell cycle |
E2F1 | 4.1↑ | cell cycle |
Chk1 | >5↑ | cell cycle |
Chk2 | >5↑ | cell cycle |
FADD | >5↑ | apoptosis |
FAF | 1.9↑ | apoptosis |
Caspase 6 | >5↑ | apoptosis |
PARP | >5↑ | apoptosis |
Ras | 1.9↑ | signal transduction |
c-Raf | >5↑ | signal transduction |
Mek2 | >5↑ | signal transduction |
ERK1 | 1.6↓ | signal transduction |
ERK2 | 1.5↑ | signal transduction |
Rsk | 2.4↑ | signal transduction |
JAK1 | >5↑ | signal transduction |
STAT1 | 1.7↑ | signal transduction |
JNK1 | >5↑ | signal transduction |
GR | 1.8↓ | signal transduction |