Table 1 Transcripts With Significant Changes In Expression After Inhibition Of NF-κB Nuclear Translocation*
From: The functional genomic response of developing embryonic submandibular glands to NF-kappaB inhibition
Function (Fig. 1) | Protein | Fold-Change | Function (Fig. 1) | Protein | Fold-Change |
|---|---|---|---|---|---|
Cell Cycle | PCNA | 1.69↓ | Cell Cycle | CyclinG1 | 1.99↑ |
|  | E2F3 | 1.86↑ |  | CyclinG2 | 2.06↑ |
|  | CyclinA2 | 1.89↑ |  | Cdk4 | 1.86↑ |
|  | CyclinB1 | 2.13↑ |  | Cdc25a | 2.00↑ |
|  | CyclinB2 | 1.91↑ |  | Bub1 | 1.58↓ |
|  | CyclinD1 | 1.64↑ |  | Bub1b | 2.33↑ |
|  | CyclinD2 | 2.45↑ |  | wee1 | 2.11↑ |
|  | CyclinE1 | 1.64↑ |  | p57 | 2.05↑ |
Apoptosis | p53 | 1.54↑ | Apoptosis | Bad | 2.00↓ |
|  | Fas | 1.79↑ |  | Bax | 1.82↑ |
|  | FasL | 3.17↓ |  | Bc12 | 1.58↑ |
|  | FAF | 2.01↑ |  | Bclx | 1.58↑ |
|  | TRAIL | 3.50↓ |  | Caspase1 | 2.03↓ |
|  |  |  |  | Caspase7 | 1.90↓ |
Signal Transduction | IGF1 | 1.83↑ | Signal Transduction | CREB1 | 1.91↑ |
|  | IGF2 | 2.33↑ |  | c-jun | 2.49↑ |
|  | IGF1R | 1.53↑ |  | c-myc | 2.47↑ |
|  | IGF2R | 1.69↑ |  | TGF-β1 | 2.03↑ |
|  | IGFBP2 | 2.27↑ |  | TGF-β2 | 2.06↑ |
|  | IGFBP3 | 2.41↑ |  | BMP1 | 2.19↑ |
|  | IGFBP4 | 1.92↑ |  | BMP3b | 2.35↑ |
|  | IGFBP5 | 1.81↑ |  | BMP8a | 1.67↓ |
|  | IGFBP6 | 2.48↑ |  | BMPR1b | 1.92↓ |
|  | FGFR.1 | 2.93↑ |  | BMPR2 | 1.87↑ |
|  | FGFR4 | 1.67↓ |  | Smad1 | 1.90↑ |
|  | Ras | 1.58↑ |  | Smad5 | 1.50↑ |
|  | B-Raf | 2.01↑ |  | Smad7 | 1.97↑ |
|  | ERK6 | 2.02↑ |  | GR | 1.67↓ |