Figure 6

Transformation of 2^nd arch identity transforms 2^nd arch wdr68 sensitivity. A, C) Lateral views at 4dpf. B, D) Ventral views at 4dpf. A, B) Wild type animal injected with mozMO transforms 2^nd arch cartilage elements into mirror image duplicates of 1^st arch cartilages. C, D) Injecting dys animals with mozMO reveals similar cartilage losses as in maternal wdr68 knockdowns shown in (Fig. 4E, F) but with further reduction of HM region presumably through mirror image duplication of the missing 1^st arch cartilages.