Figure 4From: Mosaic analysis of stem cell function and wound healing in the mouse corneal epitheliumAnalysis of stripe patterns in the corneal epithelium. A. Qualitative classification of stripe patterns at different ages. Eyes were classed as having a clockwise (n = 61) or anticlockwise whorl (n = 53), a midline (n = 21) or no clear pattern (n = 51). There was no change in the proportions of clockwise and anticlockwise patterns with age (χ2 test; P > 0.05). B: Comparison of observed and expected frequencies of whorl phenotypes (a-i) in left and right eyes of 56 mice. Animals with unclear patterns in either eye were excluded. There was no significant difference between observed and expected frequencies (χ2 test; P > 0.05) implying that there was no association between the phenotypes of the left and right eyes. Phenotype combinations: (a), clockwise (CW) left (L) plus CW right (R); (b), CW-L plus anticlockwise (ACW) R; (c), CW-L plus midline (ML) R; (d), ACW-L plus CW-R; (e), ACW-L plus ACW-R; (f), ACW-L plus ML-R; (g), ML-L plus CW-R; (h), ML-L plus ACW-R; (i), ML-L plus ML-R. The expected numbers of mice for each phenotype pair were calculated by multiplying the product of the two appropriate individual overall frequencies (CW = 0.455, ACW = 0.402 and ML = 0.143) by the number of pairs of eyes. For example, the expected number of mice with one CW and one ACW whorl is 0.455 × 0.402 × 56 = 10.25.Back to article page