Figure 8From: O-GlcNAc modifications regulate cell survival and epiboly during zebrafish developmentMesodermal derivatives are disorganized in Ogt expressing embryos. Images of fixed embryos processed for in situ hybridization to reveal expression of ntl at 10 hpf (A-C) or MyoD at 14 hpf (D-F). At 10 hpf, ntl is expressed in the axial mesoderm in controls (A). ntl expression is truncated (B) in class I embryos, and more severely truncated in class II embryos (C). MyoD marks trunk somites on either side of the midline at 14 hpf (D). Some somites are missing in class I embryos, but many of the remaining somites are abnormally wide (E). In class II embryos, somites extend around the circumference of the embryos (F).Back to article page