Table 3 Networks generated from IPA for Oct-4-regulated genes.*
From: Maternal Oct-4 is a potential key regulator of the developmental competence of mouse oocytes
Network | Molecules in Network | Score | Focus Molecules | Top Functions |
|---|---|---|---|---|
1 | Bat1, Cd58, Cpd, Ddx11, Ddx21, Dleu1, Dleu2, Dub2, Duox2, E2f1, Exosc9, Hivep3, Hn1, Il2, Jun, Mfap1, Mist, Myc, Nr2e1, Parp1, Prl2c2, Psat1, Psmc5, Psmd6, Psmd7, Ranbp1, Rbm14, Rps16, Rps18, Sec61g, Terf2ip, Tle4, Tmem126a, Trip4, Vhl | 28 | 12 | Gene Expression, Cell Death, Hematological Disease |
2 | Aatk, Bpi, Cdh1, Cldn11, Ctsc, Dhrs3, Dlx1, Eef1d, Foxd3, Gfra1, Hoxa7, Iqgap1 (Includes Eg:8826), Kif3c, Mc1r, Mt1l, Nif3l1, Nkx2-3, Nrtn, Ogn, Optn, Pik3c3, Pla2g7, Pou5f1, Psmb2, Psmb9, Ptpru, Retinoic Acid, Rna Polymerase Ii, Serpinb8, Slc12a6, Tmem49, Tmsb10, Tnf, Zfp42, Zfp36l1 | 15 | 7 | Cancer, Reproductive System Disease, Cell Death |
3 | Cd79a, Mro | 3 | 1 | Lipid Metabolism, Small Molecule Biochemistry, Viral Function |
4 | Cggbp1, Fmr1 | 3 | 1 | Connective Tissue Development and Function, Developmental Disorder, Genetic Disorder |
5 | Pgm, Pgm2, Pmm | 3 | 1 | Carbohydrate Metabolism, Small Molecule Biochemistry |
6 | Arsa, Arsb, Arsd, Arse, Arsf, Arsg, Arsi, Arsj, Gns, Ids, Sgsh, Sts, Sulf1, Sulf2, Sumf1 | 2 | 1 | Genetic Disorder, Metabolic Disease, Skeletal and Muscular System Development and Function |