Figure 6
From: KIT is required for hepatic function during mouse post-natal development
Misregulation of VldlR , Lipin1 and Lpl , in the liver of Sco5 mutants compared to controls. At 2.5 dpp, a significant dowregulation of Lpin1 is observed in mutant (open rectangle) compare to wild type (filled rectangle) while Vldlr is significantly downregulated at 1.5 dpp. At 10.5 dpp, the expression level of VldlR, Lipin1 and Lpl is low in mutant compare to wild-type livers whereas the expression of Lipc is not affected. All the data were normalized as described in the Materials and Methods and were subjected to statistical analysis (Fischer and Student t tests, * for p < 0.05 and ** for p < 0.01).