Figure 8
From: Novel gene expression patterns along the proximo-distal axis of the mouse embryo before gastrulation
Predicted primary and secondary structures of Talia aligned with the known structure of HuD protein [28]. Dashes are introduced for the purpose of alignment. Talia shows a similar arrangement of predicted α-helices (open rods) and β-strands (closed rods) to that of HuD, which contains two repeated β1-α1-β2-β3-α2-β4 motifs separated by a linker region, and strongly suggests a similar function to HuD in binding to the 3' UTRs of mRNAs. High divergence in primary structure, however, suggests they differ in their target sequences.