Figure 5
SDF-1 promotes axon elongation and branching in cortical neurons. (a-f) Representative reconstructions of GFP labeled neurons in SDF-1 treated (a-c) and control (d, e) cultures; note the elongated and branched axons in SDF-1 treatment compared to shorter axons in controls (arrows). (f) Graph illustrates the average length of GFP+ axons in control and treated cultures. (g) Stacked graph shows the frequency of branching in control and treated cultures. Scale bar: 90 μm. ****: Significance at p < 0.0001 (chi-square test).