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Table 1 Heteroplasmy in tissues of ovine fetuses and sheep cloned by SCNT from fetal fibroblasts

From: Mitochondrial DNA heteroplasmy in ovine fetuses and sheep cloned by somatic cell nuclear transfer

Clone

% donor mtDNA in tissues analysed

Source

CA1

n.d. in blood, skin

lamb

CA2

blood (0.3), skin (0.3)

lamb

CA3

blood (0.6), skin (0.7)

lamb

CA4

n.d. in skin, tongue

fetus

CA5

brain (46.5), intestine (14.4), kidney (26.2), liver (11), lung (18.4), testis (6.8), tongue (10.4)

fetus

CA6

n.d. in amnion, blood, cerebellum, chorioallantois, heart, kidney, liver, lung, muscle, skin, small intestine, umbilicus

lamb

CA7

n.d. in placenta, skin, tongue

fetus

CB1

n.d. in cells at passage 2

fetus

CB2

cells at passage 2 (0.1)

fetus

CB3

cells at passage 2 (0.2)

fetus

CC1

cells at passage 0 (0.9)

fetus

CC2

skin (0.2), brain (0.3), hind limb muscle (0.2); n.d. in ileum, kidney, liver, lung, spleen, testis

lamb

  1. n.d., not detectable