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Figure 4 | BMC Developmental Biology

Figure 4

From: The first trimester human trophoblast cell line ACH-3P: A novel tool to study autocrine/paracrine regulatory loops of human trophoblast subpopulations – TNF-α stimulates MMP15 expression

Figure 4

Heatmap analysis of microarray data showing hierarchical clustering of 832 differentially expressed genes between first trimester primary trophoblasts, AC1-1 and ACH-3P cells. Three first trimester primary trophoblast preparations (FT 1, 2, 3), two AC1-1 (AC1-1 1, 2) and two ACH-3P (ACH-3P 1, 2) RNA preparations were analyzed. Red or green colours indicate differentially up- or downregulated (619) genes, respectively (FC > 2 fold). The dendrogram displayed on top was based on hierarchical clustering of the samples using the average linkage method indicating the strong relation of the ACH3P cell line with the primary cells.

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