Figure 2
Neurons and astroglia in a pair of wildtype and transchromosomic teratomas from the same animal. The presence of the two main cell types of the differentiated neuroectoderm, neurons and astroglia, within the tumours was visualised by fluorescence immunocytochemistry. Paraffin-embedded sections of wildtype (D3) and transchromosomic (47-1) tumours were stained with antibodies specific for neuronal (MAP-2), and glial (GFAP) proteins. Transchromosomic tumours contained far fewer glia and neurons than wildtype tumours. A, D3 tumour at low magnification; B, high magnification photo of the same D3 tumour; C, 47-1 tumour at low magnification; D, high magnification photo of the same 47-1 tumour.