Activated AKT/PKB signaling in C. elegansuncouples temporally distinct outputs of DAF-2/insulin-like signaling

Table 2 Adult lifespan of age-1(mg109) dauer arrest suppressors.

^a Lifespan assays performed at 25°C
^b These are homozygote progeny of age-1(mg109) homozygous hermaphrodites that have been maternally rescued for dauer arrest [27].
^c Although the akt-1(mg247) allele increased mean lifespan compared to age-1(mg109) control animals, the median lifespan and maximum lifespan was not significantly affected (age-1(mg109)^{a, b}, 25 days median, 32 days maximum; age-1(mg109);akt-1(mg247)^a, 24 days median, 33 days maximum, Figure 4)
^d Wilcoxan P value = 0.2370.
^f Lifespan assays performed at 20°C.
^g P vs age-1(mg109)^{a, b}
SE, Standard error.
n indicates the number of animals scored in at least three independent trials.

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