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Figure 2 | BMC Developmental Biology

Figure 2

From: Expression patterns of plexins and neuropilins are consistent with cooperative and separate functions during neural development

Figure 2

Expression of plexins and neuropilins in the spinal cord at stage 18 analyzed by in situ hybridization. PlexinA1, A2, and B1 were detectable with very similar patterns in the dorsal spinal cord at stage 18, the earliest stage we investigated (arrowheads). PlexinA1 and A2 were also expressed in early motor neurons of the ventral spinal cord (open arrowheads). PlexinA2, B1 and C1 were the only plexins expressed in the floor plate (open arrow). In contrast to plexinA1 and A2, npn-1 (NP1) was expressed only in motor neurons that had migrated laterally (arrow). Npn-2 (NP2) was expressed at low levels in the dorsal spinal cord similar to plexinA1, A2, and B1 (arrowhead). Adjacent sections hybridized with the respective sense probes are shown in [Additional file 1]. Bar 50 μm.

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BMC Developmental Biology

ISSN: 1471-213X

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