Figure 3
Expression of tau-GFP in DTy54 transgenic mice at E14.5. (A-E) Sections showing tau-GFP in the eye and optic tract. The optic nerve (on) contains tau-GFP (B-D). Axons containing tau-GFP are seen emerging from the retina at the optic nerve head (C) and forming the optic chiasm (E). (F) Parasagittal section through the brain at E14.5 showing tau-GFP in the cerebral cortex (cc), prethalamus (pth), pretectum (pt), optic chiasm (oc), basal plate of the pons (po) and primordial cerebellum (c). Arrow points to the posterior boundary of the pretectum. (G-I) Coronal sections at E14.5 showing tau-GFP in the brain: (G) the pineal gland, (H) the pallium (p), subpallium (sp) and prethalamus and (I) the cerebral cortex. (J) Section through the olfactory epithelium (oe). (K-M) Expression of Pax6 shown with immunohistochemistry on coronal sections. Scale bars: A,B 200 μm; C, 20 μm; D,E,G,H,J-L, 300 μm; F,M, 900 μm; I, 50 μm.