Figure 6

Diploid pluripotent EC cell line NTera2 and karyotypically abnormal hESC line BG01V can be distinguished from normal hESCs using Illumina array. Comparison of NTera2 and pooled hESC sample resulted a correlation coefficient of 0.8997. Two lists of genes, which were specifically expressed in NTera2 (C) or in hESCs (E) were identified. Likewise, while sharing similarities with BG01 (B, correlation coefficient= 0.9043), BG01V was different from BG01 in expression for many genes, particularly genes from the TGFβ pathway (D, F). Black dots represent genes that were detected at >0 expression level, blue dots represent genes that were detected both at > 0 expression level and at >0.99 confidence. Genes plotted outside the two thin red lines were detected at >2.5- fold difference.