Figure 5From: FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesisEnhanced or abrogated FGF10/FGFR2b signaling modulates cell proliferation. The cell proliferation index of E13 + 3 explants was calculated as the number of PCNA positive epithelial cells/total epithelial cells. Exogenous FGF10 peptide induced a significant 78% (P < 0.0001) increase, and FGFR2b-Fc chimera resulted in a significant 32% (P < 0.001) decrease, in cell proliferation compared to control.Back to article page