Figure 3From: FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesisHypoplastic SMGs are seen in Fgfr2b and Fgf10 heterozygous mice. A. Newborn WT Fgfr2b+/+ SMG. B. Newborn Fgfr2b+/- heterozygous SMG. C. Newborn WT Fgf10+/+ SMG. D. Newborn Fg10+/- heterozygous SMG. WT Fgfr2b+/+ (A) and Fgf10+/+ (C) mice exhibit Late Terminal Bud Stage SMGs consisting of ducts and terminal buds displaying distinct lumina. In contrast, fewer ducts and terminal buds are seen in Fgfr2b+/- (B) and Fg10+/- (D) heterozygous SMGs compared to WT littermates. Bar, 50 μm.Back to article page