Multiple transcription factors directly regulate Hox gene lin-39 expression in ventral hypodermal cells of the C. elegans embryo and larva, including the hypodermal fate regulators LIN-26 and ELT-6

Table 1 Seven transcription factors interact with lin-39 genomic DNA in yeast one-hybrid assays

Fragment	ECRs	Size	TFs bound
YF1	ECR1	342	NHR-43
YF2	ECR2	311	ALR-1
YF3	ECR4	253
YF4	ECR7 - 10	372	ZTF-17, LIN-26
YF5	ECR11,12	298
YF6	ECR16	304
YF7	ECR17	158
YF8	ECR18 - 20	331
YF9	ECR21 - 23	257	TBX-9
YF10	ECR24 - 26	319	BED-3
YF11	ECR27,28	254
YF12	ECR29 - 33	455
JW3.9	-	338	ELT-6

The table indicates the 13 fragments (YF1-12, JW3.9) used in yeast one-hybrid screens, the evolutionarily-conserved regions (ECRs) each contains, the size of the fragment used, and the transcription factors identified as binding to each fragment.

ISSN: 1471-213X