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Figure 2 | BMC Developmental Biology

Figure 2

From: β-catenin/Tcf-signaling appears to establish the murine ovarian surface epithelium (OSE) and remains active in selected postnatal OSE cells

Figure 2

ß-catenin/Tcf-mediated lacZ expression is maintained in the embryonic female gonad. Time course of ß-catenin/Tcf-mediated transcription in female (upper panels) and male (lower panels) embryonic gonads. Whole-mount X-gal staining demonstrates ß-catenin/Tcf expression is sexually dimorphic from E12.5 onwards. Blue (lacZ) staining reflecting ß-catenin/Tcf-mediated transcription is observed in the mesonephric tubules (MT), mesonephric duct (MD), Mullerian duct (MU), Wolffian duct (WD), ovaries (o) and testis (t). Black arrows indicate the anterior region of the female gonad. Arrowhead indicates the ventral surface and posterior tip of the male gonad. All gonads are positioned with the anterior region at the top of each panel. Scale bar = 10 μm.

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BMC Developmental Biology

ISSN: 1471-213X

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