Figure 4From: β-catenin/cyclin D1 mediated development of suture mesenchyme in calvarial morphogenesisFGF and BMP signaling is stimulated by sβ-cat in the developing suture. Immunostaining analysis reveals that β-catenin gain-of-function mutation alters the population of the β-catenin (A, B), Fgfr1 (C, D), Fgfr2 (E, F), Fgf2 (G, H) and phosphorylated Smad1/5/8 (I, J) expressing cells in the metopic suture at one week after birth. The broken lines define the suture region. (K) Graph shows the average percentage of positive stained cells in the controls and mutants (mean + SEM). Scale bars, 50 μm (A-J).Back to article page