Skip to content



This section considers studies in the development of organs and tissues.

Page 3 of 3
  1. Content type: Research article

    Secreted frizzled-related proteins (SFRPs) are a family of proteins that block the Wnt signaling pathway and loss of SFRP1 expression is found in breast cancer along with a multitude of other human cancers. Ac...

    Authors: Kelly J Gauger, Akihiko Shimono, Giovanna M Crisi and Sallie Smith Schneider

    Citation: BMC Developmental Biology 2012 12:25

    Published on:

  2. Content type: Research article

    Valvulogenesis and septation in the developing heart depend on the formation and remodeling of endocardial cushions in the atrioventricular canal (AVC) and outflow tract (OFT). These cushions are invaded by a ...

    Authors: Kathryn E LeMasters, Yotam Blech-Hermoni, Samantha J Stillwagon, Natalie A Vajda and Andrea N Ladd

    Citation: BMC Developmental Biology 2012 12:22

    Published on:

  3. Content type: Research article

    The lung and thyroid are derived from the anterior endoderm. Retinoic acid and Fgf signalling are known to be essential for development of the lung in mouse but little is known on how the lung and thyroid are ...

    Authors: Jean H Wang, Steven J Deimling, Nicole E D'Alessandro, Lin Zhao, Fred Possmayer and Thomas A Drysdale

    Citation: BMC Developmental Biology 2011 11:75

    Published on:

  4. Content type: Research article

    We recently identified Rbm24 as a novel gene expressed during mouse cardiac development. Due to its tightly restricted and persistent expression from formation of the cardiac crescent onwards and later in forming...

    Authors: Samantha Maragh, Ronald A Miller, Seneca L Bessling, David M McGaughey, Marja W Wessels, Bianca de Graaf, Eric A Stone, Aida M Bertoli-Avella, John D Gearhart, Shannon Fisher and Andrew S McCallion

    Citation: BMC Developmental Biology 2011 11:62

    Published on:

  5. Content type: Research article

    Valuable insights into the complex process of retinal vascular development can be gained using models with abnormal retinal vasculature. Two such models are the recently described mouse lines with mutations in La...

    Authors: Malia M Edwards, D Scott McLeod, Rhonda Grebe, Céline Heng, Olivier Lefebvre and Gerard A Lutty

    Citation: BMC Developmental Biology 2011 11:60

    Published on:

  6. Content type: Research article

    Sox6 is a multi-faceted transcription factor involved in the terminal differentiation of many different cell types in vertebrates. It has been suggested that in mice as well as in zebrafish Sox6 plays a role i...

    Authors: Chung-Il An, Yao Dong and Nobuko Hagiwara

    Citation: BMC Developmental Biology 2011 11:59

    Published on:

  7. Content type: Research article

    During liver development, intrahepatic bile ducts are thought to arise by a unique asymmetric mode of cholangiocyte tubulogenesis characterized by a series of remodeling stages. Moreover, in liver diseases, ce...

    Authors: Peter S Vestentoft, Peter Jelnes, Branden M Hopkinson, Ben Vainer, Kjeld Møllgård, Bjørn Quistorff and Hanne C Bisgaard

    Citation: BMC Developmental Biology 2011 11:56

    Published on:

  8. Content type: Research article

    Nkx2.2 and Arx represent key transcription factors implicated in the specification of islet cell subtypes during pancreas development. Mice deficient for Arx do not develop any alpha-cells whereas beta- and delta...

    Authors: Simon Kordowich, Patrick Collombat, Ahmed Mansouri and Palle Serup

    Citation: BMC Developmental Biology 2011 11:52

    Published on:

  9. Content type: Research article

    In a recent genomic study, Leung et al. used a factorial microarray analysis to identify Smarca4 (Brg1)-regulated genes in micro-dissected zebrafish retinas. Two hundred and fifty nine genes were grouped in th...

    Authors: Monica R Hensley, Farida Emran, Sylvia Bonilla, Liyun Zhang, Wenxuan Zhong, Paul Grosu, John E Dowling and Yuk Fai Leung

    Citation: BMC Developmental Biology 2011 11:45

    Published on:

  10. Content type: Research article

    Sphingosine-1-phosophate (S1P) is a biologically active sphingolipid metabolite that influences cellular events including differentiation, proliferation, and migration. S1P acts through five distinct cell surf...

    Authors: Ryan R Poulsen, Carolyn M McClaskey, Scott A Rivkees and Christopher C Wendler

    Citation: BMC Developmental Biology 2011 11:37

    Published on:

  11. Content type: Research article

    Paraxial protocadherin (PAPC) plays a crucial role in morphogenetic movements during gastrulation and somitogenesis in mouse, zebrafish and Xenopus. PAPC influences cell-cell adhesion mediated by C-Cadherin. A...

    Authors: Barbara Jung, Almut Köhler, Alexandra Schambony and Doris Wedlich

    Citation: BMC Developmental Biology 2011 11:36

    Published on:

  12. Content type: Research article

    The Drosophila wing represents a particularly appropriate model to investigate the developmental control of phenotypic variation. Previous studies which aimed to identify candidate genes for wing morphology demon...

    Authors: Valeria P Carreira, Ignacio M Soto, Julián Mensch and Juan J Fanara

    Citation: BMC Developmental Biology 2011 11:32

    Published on:

Page 3 of 3

2016 Journal Metrics

  • Citation Impact
    2.280 - 2-year Impact Factor
    2.616 - 5-year Impact Factor
    0.708 - Source Normalized Impact per Paper (SNIP)
    1.353 - SCImago Journal Rank (SJR)

    1092.5 Usage Factor

    Social Media Impact
    43 Mentions