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BMC Developmental Biology

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Organogenesis

This section considers studies in the development of organs and tissues.

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  1. Content type: Methodology article

    Mapping of tissue structure at the cellular, circuit, and organ-wide scale is important for understanding physiological and biological functions. A bio-electrochemical technique known as CLARITY used for three...

    Authors: Hyunsu Lee, Jae-Hyung Park, Incheol Seo, Sun-Hyun Park and Shin Kim

    Citation: BMC Developmental Biology 2014 14:48

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  2. Content type: Research article

    Identification and characterization of molecular controls that regulate mammary stem and progenitor cell homeostasis are critical to our understanding of normal mammary gland development and its pathology.

    Authors: Gautam K Malhotra, Xiangshan Zhao, Emily Edwards, Janel L Kopp, Mayumi Naramura, Maike Sander, Hamid Band and Vimla Band

    Citation: BMC Developmental Biology 2014 14:47

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  3. Content type: Research article

    In standard cell division, the cells undergo karyokinesis and then cytokinesis. Some cells, however, such as cardiomyocytes and hepatocytes, can produce binucleate cells by going through mitosis without cytoki...

    Authors: Kiichiro Taniguchi, Akihiko Kokuryo, Takao Imano, Ryunosuke Minami, Hideki Nakagoshi and Takashi Adachi-Yamada

    Citation: BMC Developmental Biology 2014 14:46

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  4. Content type: Research article

    The switch from cartilage template to bone during endochondral ossification of the growth plate requires a dynamic and close interaction between cartilage and the developing vasculature. Vascular invasion of t...

    Authors: Sonja M Walzer, Erdal Cetin, Ruth Grübl-Barabas, Irene Sulzbacher, Beate Rueger, Werner Girsch, Stefan Toegel, Reinhard Windhager and Michael B Fischer

    Citation: BMC Developmental Biology 2014 14:36

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  5. Content type: Methodology article

    Morphometric quantification of subtle craniofacial variation in studies of experimentally modified embryonic mice has proved valuable in determining the effects of developmental perturbations on craniofacial m...

    Authors: Christopher J Percival, Rebecca Green, Ralph Marcucio and Benedikt Hallgrímsson

    Citation: BMC Developmental Biology 2014 14:31

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  6. Content type: Research article

    The Drosophila heart (dorsal vessel) is a relatively simple tubular organ that serves as a model for several aspects of cardiogenesis. Cardiac morphogenesis, proper heart function and stability require structural...

    Authors: Dominik Hollfelder, Manfred Frasch and Ingolf Reim

    Citation: BMC Developmental Biology 2014 14:26

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  7. Content type: Research article

    The DNA damage-mediated cell cycle checkpoint is an essential mechanism in the DNA damage response (DDR). During embryonic development, the characteristics of cell cycle and DNA damage checkpoint evolve from a...

    Authors: Xiao Qi Wang, Kwok Kin Chan, Xiaoyan Ming, Vincent CH Lui, Randy YC Poon, Chung Mau Lo, Chris Norbury and Ronnie TP Poon

    Citation: BMC Developmental Biology 2014 14:23

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  8. Content type: Research article

    The outermost layer of the vertebrate heart, the epicardium, forms from a cluster of progenitor cells termed the proepicardium (PE). PE cells migrate onto the myocardium to give rise to the epicardium. Impaire...

    Authors: Jessica S Plavicki, Peter Hofsteen, Monica S Yue, Kevin A Lanham, Richard E Peterson and Warren Heideman

    Citation: BMC Developmental Biology 2014 14:18

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  9. Content type: Research article

    The development of blood flow in the heart is crucial for heart function and embryonic survival. Recent studies have revealed the importance of the extracellular matrix and the mechanical stress applied to the...

    Authors: Tomomi Watanabe-Asaka, Yoshio Sekiya, Hironori Wada, Takako Yasuda, Ikuya Okubo, Shoji Oda and Hiroshi Mitani

    Citation: BMC Developmental Biology 2014 14:12

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  10. Content type: Research article

    Flatfish metamorphosis is a hormone regulated post-embryonic developmental event that transforms a symmetric larva into an asymmetric juvenile. In altricial-gastric teleost fish, differentiation of the stomach...

    Authors: Ana S Gomes, Yuko Kamisaka, Torstein Harboe, Deborah M Power and Ivar Rønnestad

    Citation: BMC Developmental Biology 2014 14:11

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  11. Content type: Research article

    Diacylglycerol kinase (DGK) is a key enzyme that regulates diacylglycerol (DG) turnover and is involved in a variety of physiological functions. The isoform DGKθ has a unique domain structure and is the sole m...

    Authors: Shuji Ueda, Becky Tu-Sekine, Minoru Yamanoue, Daniel M Raben and Yasuhito Shirai

    Citation: BMC Developmental Biology 2013 13:35

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  12. Content type: Research article

    Ecdysone triggers transcriptional changes via the ecdysone receptor (EcR) to coordinate developmental programs of apoptosis, cell cycle and differentiation. Data suggests EcR affects cell cycle gene expression...

    Authors: Naomi C Mitchell, Jane I Lin, Olga Zaytseva, Nicola Cranna, Amanda Lee and Leonie M Quinn

    Citation: BMC Developmental Biology 2013 13:28

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  13. Content type: Database

    The vertebrate craniofacial skeleton may exhibit anatomical complexity and diversity, but its genesis and evolution can be understood through careful dissection of developmental programs at cellular resolution...

    Authors: B Frank Eames, April DeLaurier, Bonnie Ullmann, Tyler R Huycke, James T Nichols, John Dowd, Marcie McFadden, Mark M Sasaki and Charles B Kimmel

    Citation: BMC Developmental Biology 2013 13:23

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  14. Content type: Research article

    Extracellular leucine-rich repeat (eLRR) proteins are a highly diverse superfamily of membrane-associated or secreted proteins. In the membrane-associated eLRR proteins, the leucine-rich repeat motifs interact...

    Authors: Chris R Gissendanner and Tram Do Kelley

    Citation: BMC Developmental Biology 2013 13:21

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  15. Content type: Research article

    MicroRNAs play important roles in regulating biological processes, including organ morphogenesis and maturation. However, little is known about specific pathways regulated by miRNA during lung development. Bet...

    Authors: Sana Mujahid, Tanya Logvinenko, MaryAnn V Volpe and Heber C Nielsen

    Citation: BMC Developmental Biology 2013 13:13

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  16. Content type: Research article

    Our current knowledge on tooth development derives primarily from studies in mice. Very little is known about gene expression and function during human odontogenesis. Sonic Hedgehog (SHH) signaling has been de...

    Authors: Xuefeng Hu, Shuo Zhang, Guimiao Chen, Chensheng Lin, Zhen Huang, YiPing Chen and Yanding Zhang

    Citation: BMC Developmental Biology 2013 13:11

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  17. Content type: Research article

    Thyroid hormones regulate growth and development. However, the molecular mechanisms by which thyroid hormone regulates cell structural development are not fully understood. The mammalian cochlea is an intrigui...

    Authors: Katherine B Szarama, Núria Gavara, Ronald S Petralia, Richard S Chadwick and Matthew W Kelley

    Citation: BMC Developmental Biology 2013 13:6

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  18. Content type: Research article

    Secreted frizzled-related proteins (SFRPs) are a family of proteins that block the Wnt signaling pathway and loss of SFRP1 expression is found in breast cancer along with a multitude of other human cancers. Ac...

    Authors: Kelly J Gauger, Akihiko Shimono, Giovanna M Crisi and Sallie Smith Schneider

    Citation: BMC Developmental Biology 2012 12:25

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2016 Journal Metrics

  • Citation Impact
    2.280 - 2-year Impact Factor
    2.616 - 5-year Impact Factor
    0.708 - Source Normalized Impact per Paper (SNIP)
    1.353 - SCImago Journal Rank (SJR)

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    1092.5 Usage Factor

    Social Media Impact
    43 Mentions

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