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Morphogenesis and Mechanobiology

This new section considers all aspects of morphogenesis including genetic and molecular basis of morphogenesis, transition from pupae/tadpole to adult - the origin and development of morphological characteristics and structures, cell-cell adhesion, cell shape and size regulation. It also considers manuscripts in mechanobiology - an emerging field of science at the interface of biology and engineering that focuses on how physical forces and changes in the mechanical properties of cells and tissues contribute to development, cell differentiation, collective cell movement, physiology, and disease, both in animals and in plants.

  1. Mammalian early development comprises the proliferation, differentiation, and self-assembly of the embryonic cells. The classic experiment undertaken by Townes and Holtfreter demonstrated the ability of dissoc...

    Authors: Jeffrey D. Tse, Robert Moore, Yue Meng, Wensi Tao, Elizabeth R. Smith and Xiang-Xi Xu

    Citation: BMC Developmental Biology 2021 21:2

    Content type: Research article

    Published on:

  2. Nitric oxide (NO) is presumed to be a regulator of metamorphosis in many invertebrate species, and although NO pathways have been comparatively well-investigated in gastropods, annelids and crustaceans, there ...

    Authors: Susanne Vogeler, Stefano Carboni, Xiaoxu Li, Nancy Nevejan, Sean J. Monaghan, Jacqueline H. Ireland and Alyssa Joyce

    Citation: BMC Developmental Biology 2020 20:23

    Content type: Research article

    Published on:

  3. The morphogenesis of the shell field is an essential step of molluscan shell formation, which exhibits both conserved features and interlineage variations. As one major gastropod lineage, the patellogastropods...

    Authors: Weihong Yang, Pin Huan and Baozhong Liu

    Citation: BMC Developmental Biology 2020 20:18

    Content type: Research article

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  4. Scaffold proteins support a variety of key processes during animal development. Mutant mouse for the MAGUK protein Discs large 5 (Dlg5) presents a general growth impairment and moderate morphogenetic defects.

    Authors: Parvathy Venugopal, Hugo Veyssière, Jean-Louis Couderc, Graziella Richard, Caroline Vachias and Vincent Mirouse

    Citation: BMC Developmental Biology 2020 20:10

    Content type: Research article

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  5. Eyespot color pattern formation on butterfly wings is sensitive to physical damage and physical distortion as well as physical contact with materials on the surface of wing epithelial tissue at the pupal stage...

    Authors: Joji M. Otaki

    Citation: BMC Developmental Biology 2020 20:6

    Content type: Research article

    Published on: