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BMC Developmental Biology

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Integrative control of development

This section considers studies in the control of developmental processes including epigenetic studies, cell signaling and systems biology approaches to developmental biology.

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  1. Content type: Research article

    The Runt-related transcription factors (Runx) are a family of evolutionarily conserved transcriptional regulators that play multiple roles in the developmental control of various cell types. Among the three ma...

    Authors: Sebastian Nieke, Nighat Yasmin, Kiyokazu Kakugawa, Tomomasa Yokomizo, Sawako Muroi and Ichiro Taniuchi

    Citation: BMC Developmental Biology 2017 17:14

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  2. Content type: Research article

    The quality and yield of duck feathers are very important economic traits that might be controlled by miRNA regulation. The aim of the present study was to investigate the mechanism underlying the crosstalk be...

    Authors: Xingyong Chen, Kai Ge, Min Wang, Cheng Zhang and Zhaoyu Geng

    Citation: BMC Developmental Biology 2017 17:12

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  3. Content type: Research article

    Nuclear receptors are a highly conserved set of ligand binding transcription factors, with essential roles regulating aspects of vertebrate and invertebrate biology alike. Current understanding of nuclear rece...

    Authors: Susanne Vogeler, Tim P. Bean, Brett P. Lyons and Tamara S. Galloway

    Citation: BMC Developmental Biology 2016 16:33

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  4. Content type: Research article

    Ion-transport mechanisms and gap junctions are known to cooperate in creating bioelectric phenomena, like pH gradients, voltage gradients and ion fluxes within single cells, tissues, organs, and whole organism...

    Authors: Julia Lautemann and Johannes Bohrmann

    Citation: BMC Developmental Biology 2016 16:24

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  5. Content type: Research article

    Insect metamorphosis relies on temporal and spatial cues that are precisely controlled. Previous studies in Drosophila have shown that untimely activation of genes that are essential to metamorphosis results in g...

    Authors: Kimberly Regna, Peri T. Kurshan, Benjamin N. Harwood, Adam M. Jenkins, Chao-Qiang Lai, Marc A.T. Muskavitch, Alan S. Kopin and Isabelle Draper

    Citation: BMC Developmental Biology 2016 16:15

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  6. Content type: Research article

    The contribution of programmed cell death (PCD) to muscle wasting disorders remains a matter of debate. Drosophila melanogaster metamorphosis offers the opportunity to study muscle cell death in the context of de...

    Authors: Yadav Kuleesha, Wee Choo Puah and Martin Wasser

    Citation: BMC Developmental Biology 2016 16:12

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  7. Content type: Research article

    Mollusca is the second largest phylum in nature. The shell of molluscs is a remarkable example of a natural composite biomaterial. Biomineralization and how it affects mollusks is a popular research topic. The...

    Authors: Mi Zhao, Yu Shi, Maoxian He, Xiande Huang and Qi Wang

    Citation: BMC Developmental Biology 2016 16:9

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  8. Content type: Research article

    The Hedgehog (Hh) signaling pathway, acting through three homologous transcription factors (GLI1, GLI2, GLI3) in vertebrates, plays multiple roles in embryonic organ development and adult tissue homeostasis. A...

    Authors: Katherine Gurdziel, Kyle R. Vogt, Gary Schneider, Neil Richards and Deborah L. Gumucio

    Citation: BMC Developmental Biology 2016 16:4

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  9. Content type: Research article

    Biliary atresia (BA) is a human infant disease with inflammatory fibrous obstructions in the bile ducts and is the most common cause for pediatric liver transplantation. In contrast, the sea lamprey undergoes ...

    Authors: Yu-Wen Chung-Davidson, Chu-Yin Yeh, Ugo Bussy, Ke Li, Peter J. Davidson, Kaben G. Nanlohy, C. Titus Brown, Steven Whyard and Weiming Li

    Citation: BMC Developmental Biology 2015 15:47

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  10. Content type: Methodology article

    Components of the limb musculoskeletal system have distinct mesoderm origins. Limb skeletal muscles originate from somites, while the skeleton and attachments (tendons and connective tissues) derive from limb ...

    Authors: Adeline Bourgeois, Joana Esteves de Lima, Benjamin Charvet, Koichi Kawakami, Sigmar Stricker and Delphine Duprez

    Citation: BMC Developmental Biology 2015 15:39

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  11. Content type: Research article

    Hox genes encode master regulators of regional fate specification during early metazoan development. Much is known about the initiation and regulation of Hox gene expression in Drosophila and vertebrates, but ...

    Authors: Wan-Ju Liu, John S Reece-Hoyes, Albertha JM Walhout and David M Eisenmann

    Citation: BMC Developmental Biology 2014 14:17

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  12. Content type: Research article

    Serotonin (5-HT) is well known as widely distributed modulator of developmental processes in both vertebrates and invertebrates. It is also the earliest neurotransmitter to appear during neuronal development. ...

    Authors: Konstantin Glebov, Elena E Voronezhskaya, Marina Yu Khabarova, Evgeny Ivashkin, Leonid P Nezlin and Evgeni G Ponimaskin

    Citation: BMC Developmental Biology 2014 14:14

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  13. Content type: Research article

    Temperature affects virtually all cellular processes. A quick increase in temperature challenges the cells to undergo a heat shock response to maintain cellular homeostasis. Heat shock factor-1 (HSF-1) functio...

    Authors: János Barna, Andrea Princz, Mónika Kosztelnik, Balázs Hargitai, Krisztina Takács-Vellai and Tibor Vellai

    Citation: BMC Developmental Biology 2012 12:32

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  14. Content type: Research article

    Oxygen sensing is a near universal signaling modality that, in eukaryotes ranging from protists such as Dictyostelium and Toxoplasma to humans, involves a cytoplasmic prolyl 4-hydroxylase that utilizes oxygen and...

    Authors: Yuechi Xu, Zhuo A Wang, Rebekah S Green and Christopher M West

    Citation: BMC Developmental Biology 2012 12:31

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  15. Content type: Research article

    Hox proteins are transcription factors involved in crucial processes during animal development. Their mode of action remains scantily documented. While other families of transcription factors, like Smad or Sta...

    Authors: Barbara Lambert, Julie Vandeputte, Sophie Remacle, Isabelle Bergiers, Nicolas Simonis, Jean-Claude Twizere, Marc Vidal and René Rezsohazy

    Citation: BMC Developmental Biology 2012 12:29

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  16. Content type: Research article

    In chondrichthyans, basal osteichthyans and tetrapods, vertebral bodies have cartilaginous anlagen that subsequently mineralize (chondrichthyans) or ossify (osteichthyans). Chondrocytes that form the vertebral...

    Authors: Anabela Bensimon-Brito, João Cardeira, Maria Leonor Cancela, Ann Huysseune and Paul Eckhard Witten

    Citation: BMC Developmental Biology 2012 12:28

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2016 Journal Metrics

  • Citation Impact
    2.280 - 2-year Impact Factor
    2.616 - 5-year Impact Factor
    0.708 - Source Normalized Impact per Paper (SNIP)
    1.353 - SCImago Journal Rank (SJR)

    Usage 
    335,246 Downloads
    1092.5 Usage Factor

    Social Media Impact
    43 Mentions

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