Advertisement
This section considers studies in the development of gametes and the processes involved in fertilization continuing to implantation.
Research article
Cathepsin B is a lysosomal cysteine protease involved in apoptosis and oocytes which have lower developmental competence show higher expression of Cathepsin B. Furthermore, expression of Cathepsin B show a dec...
BMC Developmental Biology 2017 17:10
Published on: 4 July 2017
Research article
Mitochondrial alternative respiratory-chain enzymes are phylogenetically widespread, and buffer stresses affecting oxidative phosphorylation in species that possess them. However, they have been lost in the ev...
BMC Developmental Biology 2017 17:9
Published on: 3 July 2017
Research article
An increase in the activity of the pituitary-gonad axis (PG-axis) and gonad development are essential for the onset of spawning migration in teleosts. In the fish Coilia nasus, gonad development and spawning migr...
BMC Developmental Biology 2016 16:42
Published on: 24 November 2016
Research article
Sex determination in mammals requires expression of the Y-linked gene Sry in the bipotential genital ridges of the XY embryo. Even minor delay of the onset of Sry expression can result in XY sex reversal, highlig...
BMC Developmental Biology 2015 15:34
Published on: 6 October 2015
Research article
The sub-cortical maternal complex (SCMC), located in the subcortex of mouse oocytes and preimplantation embryos, is composed of at least four proteins encoded by maternal effect genes: OOEP, NLRP5/MATER, TLE6 ...
BMC Developmental Biology 2014 14:40
Published on: 25 November 2014
Research article
Hundreds of HSP40s derived from various species have been identified, of which several proteins are involved in spermatogenesis. DNAJB13 is a type II HSP40/DnaJ protein. In a previous study, we cloned mouse Dnajb...
BMC Developmental Biology 2014 14:38
Published on: 19 September 2014
Erratum
BMC Developmental Biology 2014 14:20
Published on: 21 May 2014
The original article was published in BMC Developmental Biology 2013 13:10
Research article
The process of fertilization involves a cell fusion event between the sperm and oocyte. Although sperm contain mitochondria when they fuse with the oocyte, paternal mitochondrial genomes do not persist in offs...
BMC Developmental Biology 2014 14:6
Published on: 15 February 2014
Research article
The injection of Neb-colloostatin into T. molitor females causes gonadoinhibitory effects on ovarian development. This peptide inhibits intercellular space formation (patency) in follicular epithelium and results...
BMC Developmental Biology 2014 14:4
Published on: 30 January 2014
Research article
It has been proven that c-kit is crucial for proliferation, migration, survival and maturation of spermatogenic cells. A periodic expression of c-kit is observed from primordial germ cells (PGCs) to spermatogenet...
BMC Developmental Biology 2013 13:38
Published on: 27 October 2013
Research article
The 14-3-3 (YWHA) proteins are central mediators in various cellular signaling pathways regulating development and growth, including cell cycle regulation. We previously reported that all seven mammalian 14-3-...
BMC Developmental Biology 2013 13:10
Published on: 1 April 2013
The Erratum to this article has been published in BMC Developmental Biology 2014 14:20
Research article
In the male germ line of Drosophila chromatin remains decondensed and highly transcribed during meiotic prophase until it is rapidly compacted. A large proportion of the cell cycle-regulated histone H3.1 is repla...
BMC Developmental Biology 2013 13:7
Published on: 22 February 2013
Research article
In mammals, R-spondin (Rspo), an activator of the Wnt/β-catenin signaling pathway, has been shown to be involved in ovarian differentiation. However, the role of the Rspo/Wnt/β-catenin signaling pathway in fis...
BMC Developmental Biology 2012 12:36
Published on: 7 December 2012
Research article
The proper balance of autophagy, a lysosome-mediated degradation process, is indispensable for oogenesis in Drosophila. We recently demonstrated that egg development depends on autophagy in the somatic follicle c...
BMC Developmental Biology 2012 12:35
Published on: 5 December 2012
Research article
Desert hedgehog (DHH) belongs to the hedgehog gene family that act as secreted intercellular signal transducers. DHH is an essential morphogen for normal testicular development and function in both mice and human...
BMC Developmental Biology 2011 11:72
Published on: 1 December 2011
Research article
Progesterone triggers resumption of the first meiotic division in the Rana pipiens oocyte by binding to the N-terminal external loop of the catalytic subunit of Na/K-ATPase, releasing a cascade of lipid second me...
BMC Developmental Biology 2011 11:67
Published on: 6 November 2011
Research article
There have been increasing attentions on the role of small RNAs, especially microRNAs in post-transcriptional gene regulation during spermatogenesis. MicroRNA-184 (miR-184) has been shown to be mainly expresse...
BMC Developmental Biology 2011 11:64
Published on: 24 October 2011
Research article
X-linked alpha thalassemia, mental retardation syndrome in humans is a rare recessive disorder caused by mutations in the ATRX gene. The disease is characterised by severe mental retardation, mild alpha-thalassem...
BMC Developmental Biology 2011 11:39
Published on: 14 June 2011
Research article
Two stages of genome activation have been identified in the mouse embryo. Specifically, minor transcriptional activation is evident at the one-cell stage and a second major episode of activation occurs at the ...
BMC Developmental Biology 2011 11:33
Published on: 3 June 2011
Research article
The gene transformer-2, which is involved in sex determination, has been studied in Drosophila, Musca, Ceratitis, Anastrepha and Lucilia. All these members of Diptera belong to the suborder Brachycera. In this wo...
BMC Developmental Biology 2011 11:19
Published on: 15 March 2011
