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Early development

Section edited by Anna-Katerina Hadjantonakis

This section considers studies in all aspects of the early development of organisms, including embryonic and somite development.

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  1. Content type: Methodology article

    Magnetic resonance imaging is a noninvasive method of evaluating embryonic development. Diffusion tensor imaging (DTI), based on the directional diffusivity of water molecules, is an established method of eval...

    Authors: Zien Zhou, Zachary DelProposto, Lianming Wu, Jianrong Xu, Jia Hua, Yan Zhou, Yongquan Ye, Zishu Zhang, Jiani Hu and E Mark Haacke

    Citation: BMC Developmental Biology 2012 12:38

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  2. Content type: Research article

    The first distinct differentiation event in mammals occurs at the blastocyst stage when totipotent blastomeres differentiate into either pluripotent inner cell mass (ICM) or multipotent trophectoderm (TE). Her...

    Authors: Manabu Ozawa, Miki Sakatani, JiQiang Yao, Savita Shanker, Fahong Yu, Rui Yamashita, Shunichi Wakabayashi, Kenta Nakai, Kyle B Dobbs, Mateus José Sudano, William G Farmerie and Peter J Hansen

    Citation: BMC Developmental Biology 2012 12:33

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  3. Content type: Research article

    Embryonic development proceeds through finely tuned reprogramming of the parental genomes to form a totipotent embryo. Cells within this embryo will then differentiate and give rise to all the tissues of a new...

    Authors: Tiphaine Aguirre-Lavin, Pierre Adenot, Amélie Bonnet-Garnier, Gaétan Lehmann, Renaud Fleurot, Claire Boulesteix, Pascale Debey and Nathalie Beaujean

    Citation: BMC Developmental Biology 2012 12:30

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  4. Content type: Research article

    During early stages of brain development, secreted molecules, components of intracellular signaling pathways and transcriptional regulators act in positive and negative feed-back or feed-forward loops at the m...

    Authors: Zsuzsa Agoston, Naixin Li, Anja Haslinger, Andrea Wizenmann and Dorothea Schulte

    Citation: BMC Developmental Biology 2012 12:10

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  5. Content type: Research article

    Cell adhesion, an integral part of D. discoideum development, is important for morphogenesis and regulated gene expression in the multicellular context and is required to trigger cell-differentiation. G-protein l...

    Authors: Hameeda Sultana, Girish Neelakanta, Francisco Rivero, Rosemarie Blau-Wasser, Michael Schleicher and Angelika A Noegel

    Citation: BMC Developmental Biology 2012 12:3

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  6. Content type: Research article

    The desmosomal cadherins (DCs), desmocollin (Dsc) and desmoglein (Dsg), are the adhesion molecules of desmosomes, intercellular adhesive junctions of epithelia and cardiac muscle. Both the DCs and desmosomes h...

    Authors: Alexander Goonesinghe, Xing-Ming Luan, Adam Hurlstone and David Garrod

    Citation: BMC Developmental Biology 2012 12:1

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    The Erratum to this article has been published in BMC Developmental Biology 2014 14:13

  7. Content type: Research article

    Genetic alterations in human topoisomerase II alpha (TOP2A) are linked to cancer susceptibility. TOP2A decatenates chromosomes and thus is necessary for multiple aspects of cell division including DNA replication...

    Authors: Beata Sapetto-Rebow, Sarah C McLoughlin, Lynne C O'Shea, Olivia O'Leary, Jason R Willer, Yolanda Alvarez, Ross Collery, Jacintha O'Sullivan, Freek Van Eeden, Carmel Hensey and Breandán N Kennedy

    Citation: BMC Developmental Biology 2011 11:71

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  8. Content type: Research article

    MicroRNAs (miRNAs) are small RNA molecules that post-transcriptionally regulate gene expression and have been shown to play an important role during development. miR-1, miR-133a, miR-133b and miR-206 are expre...

    Authors: Andrie Koutsoulidou, Nikolaos P Mastroyiannopoulos, Denis Furling, James B Uney and Leonidas A Phylactou

    Citation: BMC Developmental Biology 2011 11:34

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  9. Content type: Research article

    The metamorphosis of the spionid polychaete Pseudopolydora vexillosa includes spontaneous settlement onto soft-bottom habitats and morphogenesis that can be completed in a very short time. A previous study on the...

    Authors: Kondethimmanahalli H Chandramouli, Flora SY Mok, Hao Wang and Pei-Yuan Qian

    Citation: BMC Developmental Biology 2011 11:31

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  10. Content type: Research article

    The transition from fertilized egg to embryo is accompanied by a multitude of changes in gene expression, and the transcriptional events that underlie these processes have not yet been fully characterized. In ...

    Authors: Liselotte Vesterlund, Hong Jiao, Per Unneberg, Outi Hovatta and Juha Kere

    Citation: BMC Developmental Biology 2011 11:30

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  11. Content type: Research article

    Consistent asymmetry of the left-right (LR) axis is a crucial aspect of vertebrate embryogenesis. Asymmetric gene expression of the TGFβ superfamily member Nodal related 1 (Nr1) in the left lateral mesoderm plate...

    Authors: Katia Carneiro, Claudia Donnet, Tomas Rejtar, Barry L Karger, Gustavo A Barisone, Elva Díaz, Sandhya Kortagere, Joan M Lemire and Michael Levin

    Citation: BMC Developmental Biology 2011 11:29

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  12. Content type: Research article

    Oocyte-derived maternal RNAs drive early embryogenesis when the newly formed embryo is transcriptionally inactive. Recent studies in zebrafish have identified the role of microRNAs during the maternal-to-embry...

    Authors: Swamy K Tripurani, Kyung-Bon Lee, Gabbine Wee, George W Smith and Jianbo Yao

    Citation: BMC Developmental Biology 2011 11:25

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  13. Content type: Research article

    Lipid rafts enriched in glycosphingolipids (GSLs), cholesterol and signaling molecules play an essential role not only for signal transduction started by ligand binding, but for intracellular events such as or...

    Authors: Ban Sato, Yohko U Katagiri, Kenji Miyado, Nozomu Okino, Makoto Ito, Hidenori Akutsu, Hajime Okita, Akihiro Umezawa, Junichiro Fujimoto, Kiyotaka Toshimori and Nobutaka Kiyokawa

    Citation: BMC Developmental Biology 2011 11:22

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  14. Content type: Research article

    We developed an efficient in vitro method to differentiate mouse ES cells into the definitive endoderm (DE) and then Pdx1-expressing pancreatic lineages using mesodermal-derived supporting cells, M15. Using this ...

    Authors: Soichiro Ogaki, Seiko Harada, Nobuaki Shiraki, Kazuhiko Kume and Shoen Kume

    Citation: BMC Developmental Biology 2011 11:13

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2016 Journal Metrics

  • Citation Impact
    2.280 - 2-year Impact Factor
    2.616 - 5-year Impact Factor
    0.708 - Source Normalized Impact per Paper (SNIP)
    1.353 - SCImago Journal Rank (SJR)

    1092.5 Usage Factor

    Social Media Impact
    43 Mentions