This section considers manuscripts on all aspects of developmental biology studied in a disease context including but not limited to developmental disorders, neurodegenerative diseases, disease modelling including iPSC disease modelling, stem cell therapy, mutational studies (including knockout mice) and gene editing in a developmental disease context.
Knockdown of hspg2 is associated with abnormal mandibular joint formation and neural crest cell dysfunction in zebrafish
Heparan sulfate proteoglycan 2 (HSPG2) encodes for perlecan, a large proteoglycan that plays an important role in cartilage formation, cell adhesion, and basement membrane stability. Mutations in HSPG2 have been ...
Citation: BMC Developmental Biology 2021 21:7