Skip to main content

Development and disease

This section considers manuscripts on all aspects of developmental biology studied in a disease context including but not limited to developmental disorders, neurodegenerative diseases, disease modelling including iPSC disease modelling, stem cell therapy, mutational studies (including knockout mice) and gene editing in a developmental disease context. 

  1. Joubert syndrome and related disorders (JSRD) and Jeune syndrome are multisystem ciliopathy disorders with overlapping phenotypes. There are a growing number of genetic causes for these rare syndromes, includi...

    Authors: L. Powell, M. Barroso-Gil, G. J. Clowry, L. A. Devlin, E. Molinari, S. A. Ramsbottom, C. G. Miles and J. A. Sayer

    Citation: BMC Developmental Biology 2020 20:26

    Content type: Research article

    Published on:

  2. Archipelago (Ago) is a Drosophila homolog of mammalian F-box and WD repeat domain-containing 7 (FBW7, also known as FBXW7). In previous studies, FBW7 has been addressed as a tumor suppressor mediating ubiquitin-d...

    Authors: Sujin Nam and Kyung-Ok Cho

    Citation: BMC Developmental Biology 2020 20:14

    Content type: Research article

    Published on: