Skip to main content

Table 2 Cardiovascular defects in Pax9:Msx1 mutant embryos at E12.5

From: Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype

Genotype

n

Absent 3rd PAA

Absent 4th PAA

Control

2

0/4

0/4

CD1-Pax9–/–

4

7/8

8/8

CD1-Pax9–/–;Msx1+/–

6a

4/12*

5/12*

  1. Embryos were assessed by μCT and the 3rd and 4th PAAs (i.e. two of each per embryo) scored for being absent in each genotype. PAA defects in CD1-Pax9–/–;Msx1+/– embryos were significantly reduced when compared to CD1-Pax9–/– embryos
  2. PAA pharyngeal arch artery
  3. *p < 0.05 (Fisher’s exact test for associations)
  4. aTwo embryos were normal with no PAA defects