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Fig. 3 | BMC Developmental Biology

Fig. 3

From: Knockdown of hspg2 is associated with abnormal mandibular joint formation and neural crest cell dysfunction in zebrafish

Fig. 3

Early neural crest cell (NCC) migration and specification are normal in morphants. a-a’ Non-injected (NI) Tg(sox10:TagRFP) larvae and hspg2 morpholino injected Tg(sox10:TagRFP) larvae (MO) (N = 6 and N = 4, respectively) were staged and fixed at the 18-somite stage. Images are scaled at 200 μm and demonstrate two lateral streams of Sox10+ migrating NCCs. b-b′ NI and MO larvae (N = 8 and N = 16 respectively) were staged and fixed at the Prim-5 stage. Images are scaled at 200 μm and demonstrate Sox10+ NCCs in the pharyngeal arches. No significant changes were found between the two groups at either timepoint. Schematic represents the two migratory NCC streams in a zebrafish larvae at 18 somites and the localization of the CNCCs in the four pharyngeal arches at the Prim-5 stage

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BMC Developmental Biology

ISSN: 1471-213X

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