Fig. 6
From: Etomoxir regulates the differentiation of male germ cells by specifically reducing H3K27ac level
Etomoxir treatment leads to down regulation downregulation of male differentiation-specific gene expression. Changes in the utilization of metabolites by cells during male PGC differentiation, and upregulated increased fatty acid oxidation regulatesregulate male PGC differentiation-related genes by controlling the level of H3K27aC. In this way, these genes are activated in specific cells at specific timetimes to regulate the differentiation of PGCs