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Fig. 2 | BMC Developmental Biology

Fig. 2

From: Etomoxir regulates the differentiation of male germ cells by specifically reducing H3K27ac level

Fig. 2

Fatty acid oxidation inhibition in a mouse model showing abnormal male germ cell differentiation. a Strategies for the use of pharmacological CPT1 receptor blockers (etomoxir). b Stereomicrographs at E14.5. c, d Confocal images of gonads at E15.5. Etomoxir-treated male gonocytes show increased incorporation of BrdU. (d are based on tests of ten embryos (samples) from each of the control and experimental groups. Bar=20 μm, **p < 0.01, ***p < 0.001, ****p < 0.0001; ns, no significance; two-tailed unpaired Student’s t-test)

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