Fig. 1

Expression pattern of ARL3 and CEP120 in the human brain during early development. Sagittal sections of 8PCW-stage human embryos stained using RNAscope to show expression of ARL3 (a) (red), CEP120 (b) (red) and KI67 (c) (red), counterstained with Methyl Green. Ai and Bi ARL3 and CEP120 are expressed within cells of the choroid plexus (arrow). (Ci) KI67 expression is minimal in the choroid plexus. Aii-Aiv and (Bii-Biv) Expression of ARL3 and CEP120 is seen in the ventricular radial glia progenitor cells including the ventricular zone of the ganglionic eminences (Aii and Bii), cerebral cortex (Aiii and Biii), and rhombic lip (Aiv and Biv). Cii-Civ Expression of KI67 is seen in the ventricular zone of the ganglionic eminences, cerebral cortex, and hindbrain