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Fig. 6 | BMC Developmental Biology

Fig. 6

From: Multiple functions of the scaffold protein Discs large 5 in the control of growth, cell polarity and cell adhesion in Drosophila melanogaster

Fig. 6

Dlg5 is essential for N-cadherin independently of its effect on polarity. a, b c mutant follicle cell clones, marked by the absence of RFP, for (a, b) Dlg5EX13c) Dlg5KG00748 and stained for a)E-Cad and b)c) N-Cad. d flip-out clone overexpressing GFP-Dlg5 and stained for N Cad. e-f staining on WT follicles of N-cad and Dlg5 . f all the cells are not exactly in the same plane and Ncad is enriched more apically than Dlg5. gDlg5EX1 mutant follicle cell clones, marked by the absence of RFP and stained for Dlg5. Note the absence of Dlg5 in WT cells at the contact of Dlg5 mutant cells (arrow). h, iNcadN19 mutant follicle cell clones, marked by the absence of RFP and stained for h) Dlg5 and i) aPKC. j) Patj53 mutant follicle cell clones, marked by the absence of RFP and stained for NCad. For all pictures scale bar is 10 μm

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