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Fig. 1 | BMC Developmental Biology

Fig. 1

From: Wingless and Archipelago, a fly E3 ubiquitin ligase and a homolog of human tumor suppressor FBW7, show an antagonistic relationship in wing development

Fig. 1

ago is necessary for development of chemosensory bristles at wing margin. In all figures, chemosensory bristles with shafts and without shafts are marked with black arrows and red arrowheads, respectively. a-f Phenotypes of chemosensory bristles in control ap-Gal4/+ (n = 32, a), ap > ago RNAi (agoHM04005, agoHMS00111) (n = 26, b, and n = 46, c), ap > ago (agoUAS.ORF, myc-ago) (n = 18, d, and n = 24, e) and ap > agoHMS00111myc-ago (n = 21, f) wings. Images were taken by focusing on sensory bristles at dorsal anterior wing margin. Proximal to the left. Portions of the wings in (a-f) are magnified in (a'-f') and further magnified images in insets are to show chemosensory bristles. g Numbers of mechanosensory and chemosensory bristles along the anterior wing margin from proximal to distal tip of the longitudinal vein 2 were counted, and the data are presented in the bar graph (***p < 0.001 and ****p < 0.0001). The blue and orange bars represent numbers of mechanosensory and chemosensory bristles, respectively. h Whole wing images as shown in Additional file: Fig. S2 were used to calculate wing size (****p < 0.0001)

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