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Table 2 Effect of embryo culture supplementation with DAPT, Jagged1 and Jagged2 on mouse embryo survival

From: Notch signaling in mouse blastocyst development and hatching

Group

n

3.5 dpc embryos n (%)

n

4.0 dpc embryos n (%)

n

4.5 dpc embryos n (%)

Control

216

200 (93%)

192

176 (92%)

127

114 (90%)

DAPT

86

77 (90%)

88

78 (89%)

26

21 (81%)

Jagged1

146

131 (90%)

128

120 (94%)

108

95 (88%)

Jagged2

102

97 (95%)

103

99 (96%)

40

32 (80%)

  1. Columns marked as n show the total number of embryos present in culture; columns marked as 3.5 dpc, 4.0 dpc and 4.5 dpc show the number of non-degenerated morphologically normal embryos progressing in culture up to that time-point