Fig. 1

LncRNA DANCR levels was down-regulated in differentiated PDLSCs. a Alizarin red staining assay was performed to measure the calcium deposits in PDLSCs and the alizarin red staining level was higher in differentiated PDLSCs compared with that in undifferentiated PDLSCs. b The expression of osteogenic differentiation marker genes (including Runx2, OCN and BMP-2) were detected by qRT-PCR, and the result showed that the expressions of Runx2, OCN and BMP-2 were significantly increased in differentiated PDLSCs, ***P < 0.001, compared with undifferentiated PDLSCs group. c The differential expressions of lncRNA were identified by microarray in differentiated and undifferentiated PDLSCs. LncRNA DANCR was markedly down-regulated. d The result of qRT-PCR showed that the expressions of DANCR was significantly decreased in differentiated PDLSCs, ***P < 0.001, compared with undifferentiated PDLSCs group