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Fig. 10 | BMC Developmental Biology

Fig. 10

From: Electrochemical gradients are involved in regulating cytoskeletal patterns during epithelial morphogenesis in the Drosophila ovary

Fig. 10

Schematic summary of effects of pHi and/or Vmem on MT (cf. Figure 9). Alkalisation (together with slight hyperpolarisation or no clear effect on Vmem) caused by furosemide, glibenclamide or 9-anthroic acid led to diffuse MT in all FC and to loss of their longitudinal alignment. This was accompanied by enhanced angles of pHi-gradients and reduced angles of Vmem-gradients (shown on the right, cf. Figure 2). Slight alkalisation together with strong hyperpolarisation as well as enhanced angles of pHi-gradients and reduced angles of Vmem-gradients (verapamil; shown on the right, cf. Figure 2) maintained the longitudinal MT-organisation. This was complemented by thickening of the MT-bundles

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