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Fig. 6 | BMC Developmental Biology

Fig. 6

From: A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos

Fig. 6

Effect of MEK and Wnt signalling pathways modulation on NANOG and SOX17 expression on day 8 bovine embryos. a Immunostaining detection of NANOG and SOX17 in representative day 8 bovine IVF blastocysts. Each image is a single optical section. Scale bar: 10 μm. b Scatter plots showing NANOG and SOX17 positive cells in control and treatments. Data were analysed by Kruskal Wallis test and are presented as Median ± IQR. Different superscripts indicate significant difference groups (p < 0.05). N: number of embryos counted after immunofluorescence detection, N = 7; 5; 6 and 6 for DMSO, 2.5 μM IWP2, 10 μM PD032 and 2.5 μM IWP2 and 10 μM PD032 groups, respectively

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