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Fig. 2 | BMC Developmental Biology

Fig. 2

From: Androgen receptor expression is required to ensure development of adult Leydig cells and to prevent development of steroidogenic cells with adrenal characteristics in the mouse testis

Fig. 2

hCG-induced expression of transcript/proteins common to most steroidogenic cells is unaffected by the absence of androgen receptors. Adult hpg, hpg.SCARKO and hpg.ARKO mice were treated daily with 4 IU of hCG (or vehicle) for 1 week. a Expression of Hsd3b1, Por, Cyp11a1 and Star was measured by qPCR and is expressed relative to Leydig cell number in each group. The presence of an asterisk (*) indicates that the effect of hCG was significant (P < 0.05) for that mouse group relative to the respective control. b and c Immunohistochemical expression of HSD3B and CYP11A1 in testes from hpg, hpg.SCARKO and hpg.ARKO mice with or without hCG treatment. The bar represent 50 μm. Primary raw data are shown in Additional file 1

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