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Table 1 Summary of pathway enrichment within each cluster

From: Short term optical defocus perturbs normal developmental shifts in retina/RPE protein abundance

Cluster name

Pathways in cluster

Significant (FDR < 0.05) pathway expression changes

Nucleocytoplasmic transport

38

24 pathways up over time in no lens & positive lens

8 pathways up over time in no lens

6 pathways up over time in positive lens

Regulation of gene expression

8

1 pathway down in negative & positive vs. no lens at 6 h, & down over time in no lens

6 pathways down in positive vs. no lens at 6 h, & down over time in no lens

1 pathway down in negative vs. no lens at 48 h

Translation

22

22 pathways down over time in no lens

Mitochondrial import

1

1 pathway down over time in no lens

rab GTPase

1

1 pathway down over time in no lens

Integration of energy metabolism

2

2 pathways down over time in no lens

Ion and vascular homeostasis

6

3 pathways up over time in negative lens, & down over time in no lens

1 pathway down in negative vs. positive lens at 6 h & 48 h

2 pathways down in negative vs. positive lens at 6 h

Signal transduction

3

1 pathway up over time in negative lens

2 pathways down over time in no lens

Solute transport

2

1 pathway down over time in no lens

1 pathway up in positive vs. no lens at 48 h