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Fig. 6 | BMC Developmental Biology

Fig. 6

From: The asymmetric cell division machinery in the spiral-cleaving egg and embryo of the marine annelid Platynereis dumerilii

Fig. 6

ACD components that convey basolateral associated polarity cues. a, b Dynamic interactions establishing basolateral Scribble complex. a Scribble interacts with Dlg and L(2)gl to antagonize aPAR complex, maintaining basolateral domain. b Scribble complex protein Dlg binds PIK3, increasing PIP3 concentration in basolateral domain. c, d. Formation of basolateral Yurt/Coracle complex. c Yurt/Coracle complex includes ion pump Na+/K+- ATPase and extracellular domain protein Neurexin IV. d Yurt antagonizes Crumbs complex by binding intracellular domain of Crumbs. e Expression profiles for components forming complexes in basolateral domain. Transcript levels for all genes are high at 2 hpf relative to later time points. na + /k + -atpase shows an increase at 4 hpf. The genes numb and brat were included with this group but are not presented in diagrams or as curves on the time (hpf) vs FPKM values graphs. Their data has been included in Additional file 5. For error bars see Additional file 11

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