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Fig. 4 | BMC Developmental Biology

Fig. 4

From: Comparison of two related lines of tauGFP transgenic mice designed for lineage tracing

Fig. 4

Non-ubiquitous and mosaic tauGFP expression. a-c Confocal images of vibratome section of adult tauGFP-positive TgTP6.4 Tg/− ovary showing that the transgene is expression in some ovarian cell types but not in the follicular granulosa cells: a tauGFP fluorescence, (b) propidium iodide (PI) counterstain and (c) combined tauGFP and PI image. d Flat mount of TgTP6.4 Tg/− cornea showing mosaic tauGFP expression. e-p Confocal images of vibratome sections of tauGFP fluorescence (e, g, i, k, m, o) and combined tauGFP fluorescence and PI counterstain (f, h, j, l, n, p), showing mosaic tauGFP expression in different TgTP6.4 Tg/− tissues and organs: (e, f) kidney, (g, h) liver, (i-l) heart and (m-p) adrenal cortex. q, r Confocal images of whole mounts of ear punch biopsies from TgTP6.4 Tg/− mice showing (q) ubiquitous and (r) mosaic tauGFP expression. s, t Mosaic tauGFP expression in two TgTP6.3 Tg/− tissues: (s) montage of flat mount of cornea and (t) vibratome section of adrenal cortex. Scale bars: e, f, g, h, k, l, o, p = 100 μm; a, b, c, q, r, t = 200 μm; i, j, m, n = 500 μm; d, s = 1000 μm

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