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Table 2 Genes up-regulated in r4-derived NCCs. Top 25 genes significantly up-regulated in the r4 NCC migratory stream as defined via Cuffdiff and EdgeR. Inf refers to an infinite Log2 fold change due to a value of 0 in r1-r2-derived NCCs

From: Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels

Gene id

r1-2

r4

log2

p value

q value

program

Hist1h2bm

38.20

28814.80

9.48

0.000112

0.034

EdgeR

Rprl2

25.60

22710.50

9.68

2.55E-06

0.004

EdgeR

Hist2h4

87.96

8685.48

6.63

0.00025

0.036

Cuffdiff

H2afj

17.84

6291.25

8.35

1.35E-05

0.010

EdgeR

Rmrp

21.77

5763.60

7.93

1.87E-05

0.012

EdgeR

Rpph1

5.23

2527.22

8.80

9.54E-06

0.008

EdgeR

Hist3h2a

6.03

2200.39

8.40

2.09E-05

0.012

EdgeR

Acta1

10.88

752.39

6.11

0.00015

0.024

Cuffdiff

Hist1h2bh

0.00

715.46

inf

0.00005

0.009

Cuffdiff

Rbp4

13.48

674.70

5.65

0.00025

0.036

Cuffdiff

Anxa2

1.52

543.21

8.36

2.85E-06

0.004

EdgeR

Afp

9.49

537.17

5.82

0.00015

0.024

Cuffdiff

Actc1

5.87

474.52

6.22

0.000129

0.034

EdgeR

Sparc

28.86

458.00

3.89

0.0002

0.049

EdgeR

Cav1

0.13

309.14

11.02

1.99E-06

0.004

EdgeR

S100a6

3.34

298.11

6.37

0.000124

0.034

EdgeR

Tgfbi

9.11

294.22

4.91

5.83E-05

0.023

Both

Krt14

0.29

286.73

9.84

1.02E-07

0.001

EdgeR

Hist1h3c

0.00

285.48

inf

0.00005

0.009

Cuffdiff

Efhd2

13.81

216.56

3.87

0.000128

0.034

Both

Ptrf

1.20

184.30

7.16

4.28E-06

0.004

EdgeR

Trnp1

1.21

174.43

7.06

8.76E-05

0.031

EdgeR

Cited4

0.22

155.37

9.28

6.87E-07

0.002

EdgeR

Des

3.64

142.70

5.18

1.50E-05

0.011

EdgeR

Serpine1

0.26

74.25

8.03

5.21E-07

0.002

EdgeR

Hoxa2

0.92

62.35

6.01

5.87E-06

0.006

EdgeR