Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels

Table 1 Genes up-regulated in r1-r2-derived NCCs. Top 25 genes significantly up-regulated in the r1-r2 NCC migratory stream as defined via Cuffdiff and EdgeR. Inf refers to an infinite Log2 fold change due to a value of 0 in r4-derived NCCs

Gene id	r1-2	r4	log2	p value	q value	program
Nkx2-9	63.19	0.00	−12.55	7.77E-07	0.002	Both
Pax5	60.65	0.71	−7.83	4.83E-05	0.021	EdgeR
Sox21	55.40	3.19	−4.04	0.000115	0.034	EdgeR
Alx3	49.60	0.05	−9.01	2.38E-07	0.001	EdgeR
Shh	41.65	1.20	−5.67	9.06E-05	0.031	EdgeR
Alx4	34.33	0.30	−6.41	1.95E-07	0.001	EdgeR
Sp8	19.00	0.19	−7.52	6.77E-06	0.006	EdgeR
Trh	13.63	0.00	inf	0.00005	0.009	Cuffdiff
Ferd3l	13.06	0.00	inf	0.00005	0.009	Cuffdiff
Gm266	13.00	0.00	inf	0.00005	0.009	Cuffdiff
Icam4	11.47	0.00	inf	0.0003	0.042	Cuffdiff
Dleu7	10.64	0.00	inf	0.00005	0.009	Cuffdiff
Alx1	8.56	0.00	inf	0.00005	0.009	Cuffdiff
Polg2	8.32	0.00	inf	0.00005	0.009	Cuffdiff
Egr4	7.94	0.00	inf	0.00005	0.009	Cuffdiff
Sp9	7.70	0.00	inf	0.00005	0.009	Cuffdiff
Tmem28	5.78	0.00	inf	0.00005	0.009	Cuffdiff
Ncf1	5.32	0.00	inf	0.00005	0.009	Cuffdiff
Ccdc92	5.31	0.00	inf	0.00005	0.009	Cuffdiff
Hemk1	4.40	0.00	inf	0.00005	0.009	Cuffdiff
Hebp2	3.97	0.00	inf	0.00005	0.009	Cuffdiff
Gabre	3.26	0.00	inf	0.0001	0.017	Cuffdiff
Katnal2	3.11	0.00	inf	0.0002	0.031	Cuffdiff
Nr2e1	2.80	0.00	inf	0.00005	0.009	Cuffdiff
Ttll9	2.66	0.00	inf	0.0001	0.017	Cuffdiff
Sh2d5	2.54	0.00	inf	0.0003	0.042	Cuffdiff

ISSN: 1471-213X