Table 1 Top networks and biological functions of Med12 regulated genes in mNSC
From: Mediator subunit Med12 contributes to the maintenance of neural stem cell identity
Top networks | Score | |
Cell-to-cell signaling and interaction, Connective tissue development and function, Cellular movement | 48 | |
Gene expression, Cell cycle, Connective tissue development and function | 38 | |
Dermatological disease and condition, Genetic disorder, Gene expression | 27 | |
Cell-to-cell signaling and interaction, Cardiac Necrosis/Cell Death, Cell death | 26 | |
Psychological disorders, Connective tissue development and function, Gene expression | 22 | |
Disease and disorders | p-value | # Genes |
Cancer | 3.02E-05–2.03E-02 | 56 |
Genetic disorder | 1.93E-04–1.88E-02 | 95 |
Endocrine system disorders | 2.17E-04–1.83E-02 | 39 |
Metabolic disease | 2.17E-04–1.83E-02 | 39 |
Hematological disease | 8.26E-04–1.83E-02 | 3 |
Molecular and cellular functions | p-value | # Genes |
Cell-to-cell signaling and interaction | 3.49E-07–1.88E-02 | 23 |
Gene expression | 2.60E-05–2.03E-02 | 15 |
Cell cycle | 6.34E-05–1.95E-02 | 13 |
Cellular development | 8.42E-05–2.03E-02 | 39 |
Cellular movement | 1.03E-04–1.98E-02 | 29 |